Evaluating Possible Mechanisms Linking Obesity to COVID-19: a Narrative Review

Obes Surg. 2022 May;32(5):1689-1700. doi: 10.1007/s11695-022-05933-0. Epub 2022 Feb 3.

Abstract

Currently, pneumonia caused by the coronavirus disease 2019 (COVID-19) is a pandemic. To date, there is no specific antiviral treatment for the disease, and universal access to the vaccine is a serious challenge. Some observational studies have shown that COVID-19 is more common in countries with a high prevalence of obesity and that people with COVID-19 have a higher body mass index. In these studies, obesity increased the risk of disease, as well as its severity and mortality. This study aimed to review the mechanisms that link obesity to COVID-19.

Keywords: Adipokines; COVID-19; Cardiovascular system; Inflammation; Insulin resistance; Obesity; Respiratory; SARS-CoV-2; Thromboembolism.

Publication types

  • Review

MeSH terms

  • COVID-19*
  • Humans
  • Obesity / complications
  • Obesity / epidemiology
  • Obesity, Morbid* / surgery
  • Pandemics
  • SARS-CoV-2